Lentils: Nutrition, Positive Aspects, And How To Cook Them
The binding of sAEL057 to iron tends to make it inaccessible to Mtb, resulting in a reduced availability of intracellular iron. This leads to an iron deprivation transcriptional response, driven by the iron-sensing transcription issue IdeR, and is demonstrated by the upregulation of mycobactin and iron import genes and downregulation of iron storage genes. In addition, we predict that catabolism of specific carbon substrates have an elevated reliance on iron-dependent proteins as compared to catabolism of other carbon substrates (such…